With the $12.5 billion purchase of Motorola Mobility, the iconic but struggling maker of mobile devices, Google has put a huge stake in the ground in this highly competitive market and thereby shaken up the entire ecosystem.

A lot of this is about patents, as Google CEO Larry Page said in his blog post about the megadeal this morning, and about acquiring a bigger portfolio that Google has long sought for its Android mobile operating system and has been unsuccessful at getting for itself, despite onerous efforts. Since Motorola has been in the mobile arena for so long, it has a large trove of important ones.

But the dramatic acquisition by Google is also a declaration that mobile is more important to it than the skein of alliances it has built for Android with phone makers worldwide, as part of its objective of making it the dominant mobile platform for smartphones and tablets globally.

While Google has been reaching out to other hardware partners to assure them, and has said they all will remain the same in Android-land, the large mobile manufacturers who have placed their trust in Google — especially Samsung or HTC — have to be wondering what to do now.

Make no mistake — they already resent Google from time to time, the way Compaq or Dell has resented Microsoft in the PC business.

But, since Google already showed favoritism to Motorola by letting them do the first Honeycomb tablet, the Xoom (although it didn’t do any good), that discomfort will only increase now.

While Google managed to get them into lockstep on today’s announcement, with a whole Web page titled “Quotes From Android Partners,” each of them using the exact same phrase “defending Android” in their quotes feels a little like they are victims of Stockholm syndrome.

Yes, we concur with everything the Borg tells us to! Defending! Android! We’re Droids too! (Calling Patty Hearst, stat!)

The impact on everyone — from Microsoft and its partner Nokia to Apple to Research In Motion and, also, to all the wireless carriers — will be felt immediately.

And, of course, by government regulators, who have watched warily as Google has marched into business after adjacent business to its core search one.

This deal — which will require approval — is sure to even further put all of Google’s businesses in the crosshairs of rivals, who will agitate for fervent investigations.

While Android has been conceived at Google and has an “autonomous unit” with the company — run by longtime mobile vet Andy Rubin — it has now entered a new and perhaps dangerous phase for all involved, including Google.

Because while such a union is not uncommon in the mobile business — Apple and RIM do software and hardware together and Google has released its own Nexus phone (made by others) — no one has done it via acquisition and in such a definitive way.

And what an acquisition it is. Or, perhaps more accurately, could be.

Please see this disclosure related to me and Google.

Related posts

• Google: We’re Spending $12.5 Billion on Motorola to ‘Protect’ Android
• Motoogle: BOOM! The Mobile Business Just Got Completely Blown Up
• Google’s Motorola Deal Will Spur Antitrust Regulators to Action
• Watch Google Android Kingpin — and Motorola Acquirer — Andy Rubin Unplugged (Video)
• Defense Spending: Google Arms Itself With Moto Patents
• Is Google’s Motorola Deal the Break That Windows Phone Needed?
• Should Google Keep Motorola’s Patents and Sell Off the Hardware Business?
• Motorola Could Get Google Closer to Your Living Room — If the Cable Guys Play Along
• U.S. Carriers Silent on Motoroogle, but France Telecom Gives It a Thumbs Up
• Google-Motorola Deal Includes $2.5 Billion Reverse Termination Fee
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(Image courtesy of the United States Department of Energy)

After running one of the more successful Silicon Valley acquisitions by Microsoft for several years, Tellme Networks founder and GM Mike McCue (pictured here) will be leaving the company at the end of June.

As part of the transition, Zig Serafin, who has been running a lot of the speech technology efforts for the software giant at its Redmond, Wash., HQ, is taking over the voice services subsidiary and all the other related units.

They will be made into a single, yet-unnamed, team with about 400 employees in total.

McCue and Serafin are now meeting with Tellme staff at its Mountain View, Calif., HQ about the changeover.

“It was time to move on, after a long and really successful time at a big company,” said McCue, in an interview with BoomTown two weeks ago. “Voice technology is an area that I think Microsoft is committed to excelling in and the new configuration will help ensure that.”

Serafin (pictured here), a 10-year Microsoft veteran, said as much in another interview yesterday. “This is an opportunity to bring together the group to allow it to innovate across Microsoft,” he said. “We really want to advance this user interface for computing.”

Serafin said he would be spending four days a week in Silicon Valley, as part of that effort, using Tellme as the center of a “whole new speech center of excellence.”

Microsoft (MSFT) has long been aiming at differentiating itself from the popular iPhone from Apple (AAPL), which has revolutionized the mobile market via its innovative touch and movement technology, by drilling down on making speech recognition technology a popular consumer application.

It bought Tellme in 2007 for $800 million as part of that effort. Competitors in the space include Google (GOOG) and Nuance.

For example, Tellme recently announced “one-button” voice access for Windows-enabled mobile phones, as well as some new technologies to improve call automation for customer service centers.

McCue has been a pioneer in the use of speech in the mobile arena, founding Tellme in 1999. Previous to Tellme, he was VP of technology at Netscape, the once-dominant browser company.

McCue said he will be taking some time off after he leaves Tellme and then plans on working on another start-up and advising companies.

Below is a picture from a 1999 board meeting at Tellme, when it was private. It includes McCue, as well as former Netscape execs Peter Currie and Mike Homer (click on image to make it larger).

And, below that, are two video interviews I did with McCue in March of last year.

One is a tour of the Tellme HQ and another is a longer chat with McCue–whom I once called the “Patty Hearst of Silicon Valley” for being so dang sunny in an Associated Press story about what life was like after a takeover by the software giant, in the midst of Microsoft’s failed attempt to buy Yahoo (YHOO).

In it, I noted that he displayed “the cheeriness of someone with acute Stockholm syndrome and $800 million in Microsoft money.”

Tellme HQ Tour:

McCue Talks About Mobile Devices: